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Treatment of reticulohistiocytosis.

The appointment of glucocorticoids is pathogenetically justified, since they inhibit the function of the reticulohistiocytic system, stimulate hematopoiesis, normalize metabolism, etc. They are prescribed for a long time - until the clinical signs of the disease disappear.

The use of anabolic drugs (dianobol, methylandrostenediol) should be carried out with some caution in order to avoid exacerbation of the pathological process (enlarged lymph nodes, tumor-like bone formations), as K. A. Moskacheva rightly warns about. Injections of gamma globulin, blood transfusions, as well as X-ray therapy on the foci of the affected bone tissue are shown.

Assign ascorbic acid, B vitamins, especially calcium pantothenate. Prevention of Abt-Letterer-Siwe disease is reduced to the protection of furadantin pills woman from various harmful exogenous influences. First of all, ionizing radiation and viral infections should be avoided, which can have an adverse effect on the fetus and contribute to the violation of the regulatory mechanisms that control the growth and reproduction of reticulohistiocytarcells.

The prognosis is unfavorable in case of nitrofurantoin to the visceral organs, the skeletal system and other tissues. With sometimes exclusively skin forms of the disease, complex therapy with the use of glucocorticoids leads to recovery. After the onset of clinical, hematological and radiological remission, due to the possibility of an exacerbation of the disease, especially with intercurrent diseases, children should be under constant dispensary observation.



a disease from the group of histiocytosis X, manifested by fever, hepatosplenomegaly, generalized enlargement of the lymph nodes, hemorrhagic purpura, lesions of the skin, mucous membranes, flat bones, lungs - see Histiocytosis X (Histiocytosis X).

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